This anti-aging serum visibly reduces a range of skin discoloration, including sunspots, age spots, post-acne marks (or post-inflammatory hyperpigmentation), and even the most persistent dark spots. Powered by Melasyl™, the newest, multi-patented La Roche-Posay ingredient, in combination with 10% Niacinamide. A first-of-its-kind discoloration treatment to visibly correct persistent dark spots with long-lasting results, while respecting the natural tone of all skin. Proven on all skin tones.*
*Based on a 10 week study on 73 women of all skin phototypes
Visibly reduces a range of skin discolorations, including sunspots, age spots, post-acne marks (or post-inflammatory hyperpigmentation)
Helps visibly correct even persistent dark spots, while respecting skin's natural tone
CLINICAL RESULTS
After 2 weeks of use:
Reveals brighter, more radiant skin
Skin imperfections look reduced*
Powerful, visibly lasting results – continues to maintain improvement
After 8 weeks of use:
90% showed dark spot reduction**
When used in regimen of Mela B3 serum with Mela B3 UV:
Visible dark spot reduction
Improvement in skin brightness and skin texture
Improves skin plumpness
*Based on a consumer study of 73 women
**After 8 weeks of use 90% of subjects showed improvement in at least one of the size and contrast of a persistent dark spot or density of dark spots, as assessed by expert grading.
Skin Concern:
Discolorations
Dark spots
Age spots, sunspots, liver spots
Post-acne marks (Post-inflammatory hyperpigmentation)
Dull, uneven skin tone
Skin Type:
All skin types
KEY INGREDIENTS
Melasyl™: New, exclusive multi-patented La Roche-Posay ingredient that visibly reduces persistent dark spots with long-lasting results. Targets discoloration while respecting the natural tone of all skin. Born from 18 years of research. Niacinamide: A form of vitamin B3, niacinamide is a water soluble vitamin. It is widely used in dermatology and is known for its ability to help visibly fade skin discoloration. Melasyl™ and Niacinamide work together to help visibly correct even stubborn dark spots Thermal Spring Water:A soothing water sourced in the town of La Roche-Posay in France and a core ingredient in most of our products. It contains a unique combination of minerals, trace elements, and a high concentration of selenium, a natural antioxidant.
Visibly corrects even stubborn dark spots with long-lasting results, while respecting the natural tone of all skin
90% showed dark spot reduction*
*After 8 weeks of use 90% of subjects showed improvement in at least one of the size and contrast of a persistent dark spot or density of dark spots, as assessed by expert grading.
RECOMMENDED FOR SKIN DISCOLORATION
Visible discoloration, dark spots, age spots, sun spots, and post-acne marks (post-inflammatory hyperpigmentation)
Uneven skin tone
Dullness and lack of radiance
DERMATOLOGIST INSIGHT
"Hyperpigmentation is a common complaint by patients, which occurs in all skin types. Mela B3 serum with Melasyl™ & Niacinamide will improve facial skin discoloration, fade dark spots, and correct uneven skin tone.“
Board Certified Dermatologist, Dr. Callender
Before After Section Heading
MELA B3 ROUTINE
Carousel Hero
AS EARLY AS 2 WEEKS
Improved skin texture & overall appearance
Brighter, more radiant skin
AS EARLY AS 4 WEEKS
Helps correct the appearance of dark spots and uneven skin tone
AS EARLY AS 12 WEEKS
Size and intensity of dark spots appears less noticeable
Helps reduce the appearance of dark spot size and intensity
Helps correct the appearance of fine lines and wrinkles
*Clinical study on N=60 women of Fitzpatrick skin type IV to VI.
DARK SPOT REGIMEN WITH MELA B3
AS EARLY AS 2 WEEKS
Improved skin texture & overall appearance
Brighter, more radiant skin
AS EARLY AS 4 WEEKS
Helps correct the appearance of dark spots and uneven skin tone
AS EARLY AS 12 WEEKS
Size and intensity of dark spots appears less noticeable
Helps reduce the appearance of dark spot size and intensity
Helps correct the appearance of fine lines and wrinkles
*Clinical study on N=60 women of Fitzpatrick skin type IV to VI.
AS EARLY AS 2 WEEKS
Improved skin texture & overall appearance
Brighter, more radiant skin
AS EARLY AS 4 WEEKS
Helps correct the appearance of dark spots and uneven skin tone
AS EARLY AS 12 WEEKS
Size and intensity of dark spots appears less noticeable
Helps reduce the appearance of dark spot size and intensity
Helps correct the appearance of fine lines and wrinkles
*Clinical study on N=60 women of Fitzpatrick skin type IV to VI.
SPF 30 Daily Anti-Aging Moisturizer for All Skin Types
Comparison chart
Frequently Asked Questions
Mela B3 Serum can be used both in your AM and PM routine. However, if you want to use the Vitamin C Serum in your routine as well, we recommend using the Vitamin C Serum in your AM routine and the Mela B3 Serum in your PM routine.
Mela B3 Serum can be used both in your AM and PM routine. However, if you want to use the Retinol B3 Serum in your routine as well, we recommend using the Mela B3 Serum in your AM routine and Retinol B3 Serum in your PM routine.
La Roche-Posay’s free skin analysis tool, MyRoutine AI, can
be used to help determine if Mela B3 Dark Spot Serum is suitable for you. The entire AI skin analysis process takes less than 3 minutes. After
uploading a selfie and answering a few questions about your skin, MyRoutine AI instantly delivers your results and personalized skincare routine.
Mela B3 Serum helps to visibly correct the appearance of dark spots and provide a more even, radiant skin tone. This first-of-its-kind discoloration treatment visibly corrects dark sports with long-lasting results, while respecting skin's natural tone.
In a study, 90% showed a reduction in the look of persistent dark spots* after 8 weeks of use of Mela B3 Serum*.
*After 8 weeks of use 90% of subjects showed improvement in at least one of the size and contrast of a persistent dark spot or density of dark spots, as assessed by expert grading.
Mela B3 serum visibly reduces a range of skin discoloration including:
Sunspots
Age spots
Post-acne marks (or post-inflammatory hyperpigmentation)
Even the most persistent dark spots
Apply the serum after cleansing and before moisturizer. It can be used in the morning and/or evening. For best results, incorporate it into your daily skincare routine consistently.
Here is a simple routine to integrate Mela B3 Serum:
Step 1: Cleanse (AM/PM) – Begin by washing your face with a exfoliating cleanser, such as Mela B3 Cleanser, to cleanse skin, while visibly reducing dark spots.
Sun exposure stimulates melanin production, which can worsen existing dark spots or trigger new ones. Using daily broad‑spectrum sunscreen (SPF 30–50+) helps prevent further pigmentation and protects the improvements you’re getting from the serum. Sunscreen acts as an essential partner to any dark‑spot treatment.
A consumer study with 73 subjects showed visible results in as early as 2 weeks with Mela B3 Serum:
skin imperfections look reduced*
powerful, visibly lasting results - continues to maintain improvement.
After 8 weeks of use, 90% showed reduction in the look of persistent dark spots**.
*Based on a consumer study of 73 women
**After 8 weeks of use 90% of subjects showed improvement in at least one of the size and contrast of a persistent dark spot or density of dark spots, as assessed by expert grading.
Mela B3 Serum targets persistent dark spots, uneven skin tone and post-acne marks using MelasylTM and Niacinamide, while Mela B3 Double Dose Treatment addresses age spots and aging concerns like wrinkles and loss of firmness by combining MelasylTM with Proxylane. Regarding texture, the serum offers a lightweight application, whereas the Double Dose Treatment provides a hydrating gel-cream consistency.
Not sure which one is right for you? MyRoutine AI, La Roche-Posay’s free skin analysis tool, can help. The entire AI skin analysis process takes less than 3 minutes. After uploading a selfie and answering a few questions about your skin, MyRoutine AI instantly delivers your results and personalized skincare routine."