Effaclar DUO Acne Spot Treatment Texture
Effaclar DUO Acne Spot Treatment 40 ML

Effaclar DUO Acne Spot Treatment

Benzoyl Peroxide Acne Spot Treatment

Effaclar DUO Acne Spot Treatment is rated 4.7 out of 5 by 109.
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Skin Concern: Acne

DUAL ACTION ACNE TREATMENT: This acne spot treatment reduces the number and severity of acne blemishes and helps clear blackheads and whiteheads. With 5.5% micronized benzoyl peroxide and micro-exfoliating lipo-hydroxy acid, this treatment provides fast, visible results in 3 days.

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  • Acne spot treatment reduces 60% of acne in 10 days
  • Dual action: reduces the number and severity of blemishes and clears blackheads/whiteheads
  • Non-drying, oil-free, fast absorbing texture
  • Can be used as a spot treatment or all over face


  • 5.5% Benzoyl Peroxide

  • Lipo-Hydroxy Acid

  • Glycerin

  • Silica

View All Ingredients


  • 2017 The Knot Beauty Awards: Face
  • 2017 InStyle Best Beauty Buys
  • 2017 Teen Vogue Online Acne Awards/Spot Treatment - Benzoyl Peroxide
  • 2016 InStyle Best Beauty Buys Awards
View All Awards

Product Safety

  • Dermatologist Tested

  • Suitable for Sensitive Skin

  • Paraben Free

  • Fragrance Free

  • Oil Free

  • View All Product Safety

    How to Use Effaclar DUO Acne Spot Treatment


    • Use after cleansing skin thoroughly
    • Apply thin layer 1-3 times daily to affected areas
    • Can be used alone or as Step 3 of the Effaclar Dermatological Acne System
    • For full directions, refer to the Drug Facts on the packaging

    Recommended for:

    • Acne blemishes
    • Blackheads and whiteheads
    • Sensitive skin

    Effaclar DUO Acne Spot Treatment Product Reviews

    Rated 5 out of 5 by from Best Anti-Acne Solution The entire Effaclar Anti-Acne range I have found to be nothing short of perfect for my skin. I use the medicated gel cleanser, clarifying solution and duo plus and my skin is clear down to my pores with no visible markings whatsoever three weeks into the regimen. I would highly recommend the product to anyone with combination skin prone to breakouts and acne. It works perfectly if used consistently. I cleanse in the morning, tone with the clarifying solution at night and use duo plus in both instances. Also, I incorporate the Anthelios sunscreen when leaving the house and it works for me.
    Date published: 2017-11-09
    Rated 4 out of 5 by from Takes time to see a difference! I have moderate acne on my forehead (small red bumps) and around my jaw line on the right side. I have pretty much used everything over the counter and with the exception of Neutrogena products nothing works. After having read such amazing reviews about DUO I bought some (along with the gel cleanser). I did not see over night results as some on here claim. It took over a week to see real results. Now I am on week 2 and still have some lightly visiable bumps on my forehead and DRY SKIN! I use the DUO lightly once in the AM and once in the PM after washing my face. It does a great job of removing the oil but it has dried my skin and now I have to use a moisturizier. Over all I am happy with the product.
    Date published: 2011-10-21
    Rated 5 out of 5 by from Effective for sensitive skin! I have combination skin that turns insanely dry in the winter and becomes oily during the summer. However, I suffer from breakouts each month and the occasional blemish. This does a great job of spot treating without irritating my sensitive skin. I'm concerned with aging, as I recently entered my mid-30s, so I am usually wary of acne products. They tend to dry out my skin or cause it to peel excessively. However, this product managed to help clear my breakouts without impacting the rest of my skin. I'm also very impressed with the fact that there is not a strong scent to it! Comparable products usually smell strongly of the ingredients, but this one is much more mild. I'd highly recommend it!
    Date published: 2018-06-24
    Rated 4 out of 5 by from Best thing I have found It's no miracle product, but I think it's the closest thing there is. I first had this given to me by my dermatologist in Korea (I trust Koreans, they have amazing skin...) and I've been using it ever since, that's about 1.5 years. Once I run out, my acne automatically gets worse so I know it does something. I also wear makeup every day which doesn't help, but recently I've been doing Duo twice a day along with Clinique Acne solutions foundation, and using the 2 cleared up my skin like I haven't seen in years. Definitely a great product.
    Date published: 2011-08-20
    Rated 5 out of 5 by from Love/Hate Relationship I really do like this cream but I have a love/hate relationship. It’s really helped reduce any acne or blackheads I had and quickly! It also can leave a burning sensation on my skin after applying, which goes away quickly. It doesn’t cause my skin to get red at all, which is a big plus. Just using a tiny bit reduces the burning sensation. I really will purchase more, along with the Effaclar Mat Daytime Moisturizer. It’s a great combo for acne prone skin. I received this item free from Influenster in order to test and review the product!
    Date published: 2018-06-27
    Rated 5 out of 5 by from THIS PRODUCT SAVED MY SKIN! In my early 20's I started to develop very painful cystic acne around my jaw line. After trying a billion different products, going to the dermatologist and using prescription medications, I was recommended La Roche-Posey's products by the Beauty Consultant at CVS. I kid you not, within a month, (in combination with Effaclar Purfying Foaming Gel Face Wash), my skin was FLAWLESS! I recommend this product to anyone struggling with acne. My skin is soft, bright and acne free. Thank you so much La Roche-Posey. You truly saved my skin.
    Date published: 2017-10-16
    Rated 4 out of 5 by from Super Impressed! I typically don’t get bad acne but when I do I haven’t ever had a solution for it. The EFFACLAR Duo has done me so much good, summer is when I see more acne and this has been perfect for at night on any acne spots. It doesn’t dry out my skin either! I definitely noticed a reduction in my blemishes. I’ve been using this for a few weeks now in combination with the matte moisturizer and the cleansing cloths. Definitely a perfect little summer bundle. I received this product complimentary for testing purposes.
    Date published: 2018-06-25
    Rated 5 out of 5 by from Never changing this product! I have been using Effaclar Duo for years, since my teenage years into my young 20s now, and I'm not changing it for any other product. It helps over night with every small pimple it may appear, or during summer with my oily skin and one or another pimple that pops. I even use it sometimes when my skin is clear and looking healthy just to prevent any breakout or anything, and it's helpful. I'm so happy to have found this product and for the fact that it never fails to deliver what I expect.
    Date published: 2018-02-19
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