• Effaclar DUO Acne Spot Treatment Texture
  • Effaclar DUO Acne Spot Treatment 40 ML

    Effaclar DUO Acne Spot Treatment

    Benzoyl Peroxide Acne Spot Treatment

    Effaclar DUO Acne Spot Treatment is rated 4.5 out of 5 by 324.
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    Skin Concern: Acne

    DUAL ACTION ACNE TREATMENT: This acne spot treatment reduces the number and severity of acne blemishes and helps clear blackheads and whiteheads. With 5.5% micronized benzoyl peroxide and micro-exfoliating lipo-hydroxy acid, this treatment provides fast, visible results in 3 days.

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    • Acne spot treatment reduces 60% of acne in 10 days
    • Dual action: reduces the number and severity of blemishes and clears blackheads/whiteheads
    • Non-drying, oil-free, fast absorbing texture
    • Can be used as a spot treatment or all over face


    • 5.5% Benzoyl Peroxide

    • Lipo-Hydroxy Acid

    • Glycerin

    • Silica

    View All Ingredients


    • 2017 The Knot Beauty Awards: Face
    • 2017 InStyle Best Beauty Buys
    • 2017 Teen Vogue Online Acne Awards/Spot Treatment - Benzoyl Peroxide
    • 2016 InStyle Best Beauty Buys Awards
    View All Awards

    Product Safety

  • Dermatologist Tested

  • Suitable for Sensitive Skin

  • Paraben Free

  • Fragrance Free

  • Oil Free

  • View All Product Safety

    How to Use Effaclar DUO Acne Spot Treatment


    • Use after cleansing skin thoroughly
    • Apply thin layer 1-3 times daily to affected areas
    • Can be used alone or as Step 3 of the Effaclar Dermatological Acne System
    • For full directions, refer to the Drug Facts on the packaging

    Recommended for:

    • Acne blemishes
    • Blackheads and whiteheads
    • Sensitive skin
    Watch Now

    Effaclar DUO Acne Spot Treatment Product Reviews

    Rated 4 out of 5 by from great acne treatment! this was a product i was a little wary of using due to my fear of benzoyl peroxide. HOWEVER, this was not at all too harsh on my skin. i was very surprised. i really like LRP's products because they are so gentle but effective. i apply this at night on only my breakouts and i find that it definitely helps my skin clear up faster. the only issue is that on my dry skin, this treatment can be a little drying. but i imagine it would work out perfectly for oilier skin than mine, which is who this product was intended for! i received this product from influenster for free for reviewing purposes.
    Date published: 2018-07-05
    Rated 5 out of 5 by from Best Anti-Acne Solution The entire Effaclar Anti-Acne range I have found to be nothing short of perfect for my skin. I use the medicated gel cleanser, clarifying solution and duo plus and my skin is clear down to my pores with no visible markings whatsoever three weeks into the regimen. I would highly recommend the product to anyone with combination skin prone to breakouts and acne. It works perfectly if used consistently. I cleanse in the morning, tone with the clarifying solution at night and use duo plus in both instances. Also, I incorporate the Anthelios sunscreen when leaving the house and it works for me.
    Date published: 2017-11-09
    Rated 5 out of 5 by from Effective for sensitive skin! I have combination skin that turns insanely dry in the winter and becomes oily during the summer. However, I suffer from breakouts each month and the occasional blemish. This does a great job of spot treating without irritating my sensitive skin. I'm concerned with aging, as I recently entered my mid-30s, so I am usually wary of acne products. They tend to dry out my skin or cause it to peel excessively. However, this product managed to help clear my breakouts without impacting the rest of my skin. I'm also very impressed with the fact that there is not a strong scent to it! Comparable products usually smell strongly of the ingredients, but this one is much more mild. I'd highly recommend it!
    Date published: 2018-06-24
    Rated 4 out of 5 by from Takes time to see a difference! I have moderate acne on my forehead (small red bumps) and around my jaw line on the right side. I have pretty much used everything over the counter and with the exception of Neutrogena products nothing works. After having read such amazing reviews about DUO I bought some (along with the gel cleanser). I did not see over night results as some on here claim. It took over a week to see real results. Now I am on week 2 and still have some lightly visiable bumps on my forehead and DRY SKIN! I use the DUO lightly once in the AM and once in the PM after washing my face. It does a great job of removing the oil but it has dried my skin and now I have to use a moisturizier. Over all I am happy with the product.
    Date published: 2011-10-21
    Rated 5 out of 5 by from This product is life changing I received La Roche-Posay Effaclar Duo Acne Spot Treatment to try for free from influenster and I couldn't be happier and yes I will be a long time customer now. I have battled with sever acne and sensitive skin my whole life being in my 30s now I figured it would just be one of those things I'd always deal with because I've tried 100s of other products and nothing worked until now I can not believe the difference in my skin in just the first week I'm now in to week two and my skin has almost completely cleared up with only traces of what was a bad cystic acne break out and no new breakouts where has this product been my whole life!?!
    Date published: 2018-06-24
    Rated 4 out of 5 by from Great spot acne treatment!! I started using this product around 2 weeks ago and I can honestly say that after the 4th day I started seeing a visible change. The Effaclar Duo Acne spot treatment helped me with my chin after I had bad breakouts. At first I would apply the treatment in the morning and at night but I found that this dried out my skin in that little patch. I switched it up and only started applying at night. I found that this still took care of my chin blemishes as well as didn’t dry out my skin. I’m going to continue using this for my skin as the results are definitely worth it to me! I also received this product for free for testing purposes.
    Date published: 2018-07-06
    Rated 5 out of 5 by from Works great! I received this product as a complimentary sample and I love it! I have acne where I touch my face and I have a nervous habit of touching my face so I tend to get icky stubborn white heads that take forever to clear up! I use this product as a spot treatment and have found it works best when your pores are OPEN so use it after a shower or use a warm wash cloth on your face to open your pores BEFORE applying it. The active ingredient in it is the peroxide so you need to allow it into your pores to clean up the bacteria causing the acne. I used this on pimples that would normally stay on my face for a week and this product clears it up in a day or two!!!
    Date published: 2018-06-27
    Rated 4 out of 5 by from Effective Acne Treatment I received this acne treatment complimentary from the Influenster La Roche-Posay Voxbox. BUT (!!) I had previously bought it about 3 years ago from Ulta in the La Roche-Posay 3-step acne kit that also included Effaclar face wash and toner. I’ve found that this is a great acne cream if you don’t need something as strong as a topical prescription. I have sensitive skin and this does not irritate it. Pro Tip: benzoyl peroxide and salicylic acid are both ingredients often used to treat acne -- I have found better results in acne reduction when using benzoyl peroxide for spot treatment and a face wash that contains salicylic acid beforehand.
    Date published: 2018-06-19
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